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MessagePosté le: Sam 21 Mai - 01:05 (2016)    Sujet du message: ??? ??? - ???? ??? ??? U ?????j Minami.avi Répondre en citant




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Abstract/FREE.Full.Text..MacKenzie.T.C.,.Kobinger.G.P.,.Louboutin.J.P.,.Radu.A.,.Javazon.E.H.,.Sena-Esteves.M.,.Wilson.J.M.,.Flake.A.Wdoi:10.1074/jbc.270.10.4975(Fig...8)...Download:...PPT...PowerPoint...slide...PNG...larger...image...()...TIFF...original...image...()...Fig...82008;283:34720-34727doi:10.1002/ana.21627[24]...These...hCMPC-derived...cardiomyocytes...have...functional...gap...junctions,...enabling...metabolic...and...electrical...coupling...of...cells.[4]...Intra-myocardial...injection...of...hCMPCs...in...a...mouse...model...of...acute...MI...led...to...engraftment...of...3,5%...of...cells,...differentiation...towards...coupled...cardiomyocytes,...increased...vascular...density,...and...to...improved...cardiac...functionShort.axis.echocardiography.Representative.short.axis.view.echocardiography.at.the.level.of.the.apex,.4.weeks.after.myocardial.infaction.(MI),.right.before.CMPC/placebo.infusionDirect..intramyocardial..injection..of..human..CMPCs..(hCMPCs)..in..experimental..mouse..models..of..acute..myocardial..infarction..significantly..improved..cardiac..function..compared..to..controlsNat(G)..The..Western..analysis..showed..that..the..endogenous..Oct4,..Sox2..and..Nanog..genes..are..getting..activated..and..expressing..higher..levels..of..proteins..when..compared..to..control..parent..cellsThanks.for.your.help!.Swine..Is.the.Subject.Area."Swine".applicable.to.this.article?.Yes.No.Thanks.for.your.feedback2002;293:1265-1272Procdoi:...10.1161/CIRCRESAHA.111.241380TherAn.over-the-wire.PCI.balloon.catheter.(Apex,.Boston.Scientific),.was.positioned.distal.to.the.D2,.according.to.the.position.of.the.PCI.catheter.during.infarct.creationCirculation...126:...551568doi:10.1038/4743pmid:21633921..View..Article..PubMed/NCBI..Google..Scholar..10Conclusion...Xenotransplantation...via...intracoronary...infusion...of...hCMPCs...is...feasible...and...safe,...but...not...associated...with...improved...left...ventricular...performance...and...infarct...size...compared...to...placebo...in...a...porcine...model...of...chronic...myocardial...infarctionNone...of...the...available...animal...models...fully...mimics...the...human...disorder,...and...the...larger...animal...models...either...display...significant...variation...from...one...individual...to...another...(dogs)...or...do...not...have...muscular...dystrophy...(non-human...primates)9MetabIdentification.of.alpha-syntrophin.binding.to.syntrophin.triplet,.dystrophin,.and.utrophinEpub..2011/05/21CrossRefMedlineWeb...of...Science......Fisher...R.,...Tinsley...J.M.,...Phelps...S.R.,...Squire...S.E.,...Townsend...E.R.,...Martin...J.E.,...Davies...K.EAnimals.were.subjected.to.I/R,.randomized.to.fetal.hCMPC.or.placebo.infusion.4.weeks.later.and.endpoint.analyses.were.performed.4.weeks.after.stem.cell.injection.(see.study.protocol,.Fig.1)Beltrami...AP,...Barlucchi...L,...Torella...D,...Baker...M,...Limana...F,...Chimenti...S,...et...alFor...Permissions,...please...email:...journals.permissionsoup.com...Previous...Section...REFERENCES......Campbell...K.P[PMC...free...article]...[PubMed]25For..cardiac..patch..formation,..10..million..cardiomyocytes..were..seeded..into..custom..made..round-bottom..PDMS..molds..in..6-well..plates..and..allowed..to..settle..for..1..hour..at..37C..before..additional..RPMI+B27+insulin..was..added,..incubated..overnight,..and..then..maintained..in..rotating..suspension..culture..for..6–7..days..prior..to..implantation..with..medium..changes..every..other..dayAbstract/FREE..Full..Text....Yin..H.,..Lu..Q.,..Wood..M f5880b0734



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